Research Compound Database

Browse our comprehensive catalog of bioactive peptides with scientific data

Research
Phase II

ARA-290

Also: Cibinetide, ARA 290, Erythropoietin Mimetic Peptide

Immune

ARA-290 is an engineered peptide derived from erythropoietin that selectively activates the tissue-protective receptor complex without stimulating red blood cell production. It is primarily researched for neuropathic pain relief, nerve repair, inflammation reduction, and metabolic support in conditions like sarcoidosis and type 2 diabetes.

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Preclinical

KPV

Also: Lys-Pro-Val, Alpha-MSH C-terminus tripeptide

Immune

KPV is a naturally occurring tripeptide (Lysine-Proline-Valine) derived from the C-terminus of alpha-MSH. It is one of the most potent anti-inflammatory peptides identified, with documented effects on gut inflammation, skin conditions, and systemic immune modulation. Its small size allows it to penetrate gut epithelium and cross the blood-brain barrier.

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Preclinical

PNC-27

Also: PNC27, p53-Derived Peptide, Antitumor Peptide PNC-27

Immune

PNC-27 is an experimental anti-cancer peptide derived from the p53 tumor suppressor protein. It is designed to selectively target and kill cancer cells by exploiting the aberrant membrane expression of HDM-2 (the p53-binding protein) that is found on the surface of cancer cells but not normal cells. Research is entirely preclinical — no human trials completed.

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Phase III Complete

Thymosin Alpha-1

Also: Tα1, Zadaxin, Thymalfasin

Immune

Thymosin Alpha-1 is a naturally occurring 28-amino acid peptide that acts as a potent immune modulator. It is the first thymic peptide to receive regulatory approval (in over 30 countries) for treatment of Hepatitis B and as an immune adjuvant. It enhances both innate and adaptive immunity.

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Preclinical

Thymosin Beta-4 (Fragment)

Also: TB4-Frag, Ac-SDKP, N-Acetyl-Seryl-Aspartyl-Lysyl-Proline

Immune

The TB-4 fragment (Ac-SDKP) is the active anti-fibrotic and cardioprotective component of Thymosin Beta-4. While full TB-500 handles actin sequestration and cell motility, Ac-SDKP specifically inhibits TGF-β-driven fibrosis and inflammation. It naturally circulates in blood and is regulated by ACE (angiotensin-converting enzyme).

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Phase II

VIP

Also: Vasoactive Intestinal Peptide, VIP-28

Immune

VIP (Vasoactive Intestinal Peptide) is a 28-amino acid neuropeptide with potent anti-inflammatory, vasodilatory, and immunomodulatory properties. It is naturally produced throughout the body and plays a critical role in regulating the autonomic nervous system, gut motility, immune tolerance, and circadian rhythm. Research interest has surged due to its potential in treating Long COVID, MCAS, dysautonomia, and autoimmune conditions.

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Preclinical

Vilon

Also: Lys-Glu, KE Peptide, Dipeptide KE

Immune

Vilon is a dipeptide immunomodulatory bioregulator that is one of the simplest peptides in the Khavinson series. Despite its tiny size (just two amino acids), it demonstrates significant immune regulatory, anti-aging, and gene-regulatory effects. Used in longevity protocols for immune system restoration and as part of comprehensive Khavinson peptide stacks.

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