KPV

Also known as: Lys-Pro-Val, Alpha-MSH C-terminus tripeptide

Immune Modulation

Preclinical

KPV is a naturally occurring tripeptide (Lysine-Proline-Valine) derived from the C-terminus of alpha-MSH. It is one of the most potent anti-inflammatory peptides identified, with documented effects on gut inflammation, skin conditions, and systemic immune modulation. Its small size allows it to penetrate gut epithelium and cross the blood-brain barrier.

Regulatory & Approval Status

Not FDA Approved

The FDA has identified no human clinical studies for KPV, and it remains an investigational substance not approved for human use.

Information compiled from FDA compounding guidance and public regulatory sources. For research and educational purposes only; not medical advice.

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