5-Amino-1MQ

Also known as: 5-Amino-1-methylquinolinium, NNMT Inhibitor

Metabolic

Preclinical

5-Amino-1MQ is a small molecule NNMT inhibitor that works by blocking the enzyme responsible for degrading NAD+ precursors in fat tissue. By inhibiting NNMT, it raises intracellular NAD+ levels, activates SIRT1 and downstream metabolic pathways, and shifts the metabolic phenotype of adipocytes — effectively reprogramming fat cells toward a leaner, more energy-consuming state.

Regulatory & Approval Status

Not FDA Approved

5-Amino-1MQ is a research-only compound with no identified human clinical trials and no FDA-approved indications.

Information compiled from FDA compounding guidance and public regulatory sources. For research and educational purposes only; not medical advice.

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