MK-677
Also known as: Ibutamoren, Ibutamoren Mesylate, L-163,191
MK-677 (Ibutamoren) is an orally active, non-peptide ghrelin receptor agonist that stimulates GH and IGF-1 secretion. It is unique among GH secretagogues in that it is taken orally and has a long duration of action (~24 hours), making it highly convenient. Extensively studied in elderly patients for GH deficiency and muscle wasting.
Regulatory & Approval Status
MK-677 (ibutamoren) has reached Phase 3 clinical trials for various indications but has not received FDA approval for human use. It is widely recognized as a research compound and is prohibited in competitive sports.
Information compiled from FDA compounding guidance and public regulatory sources. For research and educational purposes only; not medical advice.